search
Front > News

Bioline looks to heart attack treatment clinical trial

27 Feb, 2011 10:39
שלח תגובה במיילGlobes' correspondent

Partner Ikaria is leading the trial under a development deal from 2009.

BiolineRX Ltd. (TASE:BLRX) will begin a pivotal clinical trial of its BL-1040 treatment following heart attacks, as part of the further clinical development. The trial is scheduled to begin in the second of 2011.

BL-1040 is injected into patients following a heart attack, and the liquid polymer is intended to help rebuild stronger heart muscle tissue. The liquid turns into a gel when it comes into contact with damaged heart tissue.

Ikaria Holdings Inc. is leading the trial under a development and commercialization agreement signed with Bioline RX in 2009.

The trial will test the safety and efficacy of the BL-1040 standard to prevent pathological changes in the heart structure, which are liable to cause heart failure in patients who have suffered acute myocardial infarction. The double-blind trial will include 270 patients, including patients given a placebo. Patients who have suffered a heart attack will be given BL-1040, and their condition will be monitored for six months after the treatment.

Bioline RX CEO Dr. Kinneret Savitsky said, "We are satisfied with the intensive continued clinical development of BL-1040 by Ikaria. BL-1040 is a proprietary product for the prevention of pathological changes in the heart. This trial is one of two pivotal partly overlapping clinical trials that Ikaria will carry out. They will include a large number of patients, in order to test the safety and efficacy of BL-1040." She added that Bioline RX would continue to work on other drugs in its portfolio and to seek other promising projects.

Bioline RX's share price rose 1.1% in early trading on the TASE to NIS 2.35, gibing a market cap of NIS 338 million.

Published by Globes [online], Israel business news - www.globes-online.com - on February 27, 2011

© Copyright of Globes Publisher Itonut (1983) Ltd. 2011

Bezalel Smotrich and Amir Yaron credit: Knesset Spokesperson and Tali Bogdanovsky Retail chains, credit card cos could soon act as banks

Israel's financial regulators have proposed that supermarket chains, credit card companies and investment houses will be able to accept deposits and offer credit.

Elbit Systems rocket launcher credit: Elbit Systems Elbit Systems wins $130m European rocket order

The order is for the supply of rockets for Elbit's Precise and Universal Launching System (PULS), which has an effective range of up to 300 kilometers.

Nvidia VP Ali Kani credit: Nvidia Nvidia intensifies efforts to compete with Mobileye

"Globes" talks to Nvidia VP and automotive team head Ali Kani about the chipmaker's autonomous vehicle activities and assesses the threat to Mobileye.

Fitch ratings agency credit: Shutterstock Fitch reaffirms Israel's A rating with negative outlook

The ratings agency said, "The negative outlook reflects rising public debt, domestic political and governance challenges and uncertain prospects for the conflict in Gaza."

Tamar rig credit: PR Sovereign Wealth Fund earned handsome returns in 2024

Israel's Sovereign Wealth Fund, known as the Citizens' Fund, had assets worth about $2 billion at the end of 2024, the Ministry of Finance reports.

Fencing goes up Petah Tikva's Segula neighborhood credit: NTA Work on Metro to begin in Petah Tikva

The first work on the Tel Aviv Metropolitan underground railways system will begin on the M2 line depot in Petah Tikva.

Startups credit: Shutterstock/NicoElNino IVC-LeumiTech: Tech fund raising jumps 24% in Q1

Israeli privately-held tech companies raised $2.13 billion in the first quarter of 2025, up 24% from the corresponding quarter of 2024, but down 12% from the preceding quarter.

Miri Regev and Yitzhak Rochberger credit: Yediot Ahronot/ Reuven Kapuchinsky and Amit Shabi Ramat Hasharon wants railway station for the Mossad

Ramat Hasharon is pushing for a station in Glilot neat the Mossad headquarters, even though a new station is also planned for Glilot South, 1.6 kilometers away.

Prime Minister Benjamin Netanyahu credit: Reuven Kastro Police call Netanyahu for testimony as aides arrested

Jonatan Urich and Eli Feldstein are being held over alleged payments received from Qatar while working in the prime minister's bureau.

Highcon chairperson Shlomo Nimrodi credit: PR Packaging tech co Highcon winding down

The company, which numbers Benny Landa and JVP among its investors, is laying off most of its workforce, having lost 99.9% of its value since its flotation.

MK Almog Cohen credit: Danny Shem-Tov, Knesset Spokesperson's Office Netanyahu halts Nevatim airport bill

Legislation mandating construction of an airport at Nevatim, near Beersheva, is ready for final Knesset approval, but the prime minister blocked it after a security cabinet meeting.

Big banks CEOs credit: Oren Dai, Jonthan Bloom and Israel Hadari Israeli banks unveil NIS 3b customer benefits package

The benefits over two years meet the target set by the Bank of Israel to ease the burden for customers, while the banks are reporting record profits.

Eilat's old airport Photo: Shutterstock Building set to begin on former Eilat airport land

2,469 housing units will be built as well as 2,776 hotel rooms, 88,000 square meters of office space and 95,000 square meters of commercial space.

Gas station in Israel credit: Tali Bogdanovsky Gasoline prices in Israel to rise Monday night

The maximum price of government price controlled 95 octane gasoline at self-service pumps in Israel will rise on Monday at midnight April 1, 2025, by NIS 0.08 per liter to NIS 7.31 per liter.

Israeli apartments Credit: Shutterstock Apartments sold and rented

A selection of recent real estate deals in Israel in Givatayim, Ra'anana, Modiin-Maccabim-Reut, Gedera, Kiryat Shemona and Ashkelon.

Fencing goes up Petah Tikva's Segula neighborhood credit: NTA The Metro is really happening

Although there are skeptics who doubt that the project will ever be realized, there are now enough signs on the ground to indicate that they are probably wrong.

Twitter Facebook Linkedin RSS Newsletters גלובס Israel Business Conference 2018